产品货号:
Z12516
中文名称:
CCR1抗体
英文名称:
Anti-CCR1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CCR1 Antibody |
指标别名 | C-C motif chemokine receptor 1;CD191;CKR-1;CKR1;CMKBR1;HM145;MIP1aR;SCYAR1;CCR1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | IHC,FCM |
基因名称 | CCR1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of mouse CCR1 (260-290aa FVSAFQDVLFTNQCEQSKQLDLAMQVTEVIA),different from the related human sequence by nine amino acids. |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene.This gene encodes a member of the beta chemokine receptor family,which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors.The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha),regulated on activation normal T expressed and secreted protein (RANTES),monocyte chemoattractant protein 3 (MCP-3),and myeloid progenitor inhibitory factor-1 (MPIF-1).Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation.Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response,and susceptibility to virus and parasite. |
Uniprot ID | P51675 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | C-C motif chemokine receptor 1 |
蛋白名全称 | C-C chemokine receptor type 1 |
推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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